Anjelica Gonzalez serves as an Associate Professor of Biomedical Engineering and part of the Vascular Biology and Therapeutics Program. Her research has focused on the development of biomimetic materials for use in investigation of immunology, inflammation and fibrosis.
Gonzalez has a dedicated interest in training the next generation of scientists to think in an interdisciplinary way and approach problems from a scientifically global perspective. With a multidisciplinary approach, the Gonzalez Lab combines organic chemistry, molecular biology, mathematics, computational modeling and image analysis to develop and use engineered scaffolds to dissect the chemo-mechanics of immunological processes. This work has led to significant advancement specific to an array of diseases and disorders, including vascular inflammation, stroke, fibrosis, and sepsis.
Gonzalez's translational research interests have led to the development of new technologies that are being deployed in underserved and low-infrastructure settings across the world. PremieBreathe, a low-cost, mobile neonatal respiratory device invented by Anjelica, has been supported by the US Agency for International Development (USAID), Bill and Melinda Gates Foundation and NCIIA/Venturewell for development and study deployment in Ethiopia.
- Overview of Current Project
Our world will look different in three years after the ongoing pandemic has ended, however, the need for versatile devices to treat respiratory distress will remain. Prior to the pandemic, respiratory distress was responsible for 3.2% of all neonatal deaths in the US, as well as affecting over 200K adults per year. We have developed a low-cost all-in-one system that can deliver sterilized, humidified, warmed, and oxygenated air to patients. If awarded by the Blavatnik Fund for Innovation at Yale, we intend to complete the remaining preclinical work and submit our device for regulatory approval within 7 months.
- Favorite Off-Time Activity
Coaching my twin 10 y.o. boys' little league baseball team is something I enjoy doing in the fall and spring. Getting to see all the kids engage in teamwork and individual development, while spending time outside running around with my boys is an experience I cherish. As they get older, and interested in football, hockey and basketball, I doubt my coaching skills are going to be in much demand!!!
- Best Advice for New Entrepreneurs
I am a huge proponent for social entrepreneurship and thinking critically about sustainability and impact of commercial innovation. Regardless of the innovation, if it is not accessible, affordable, sustainable and available to a wide market base, you lose opportunity for broad and meaningful impact. The more savvy every consumer base becomes, the more concerned they are about ethical considerations of the companies, products and services they use. Therefore, being forward thinking about how your innovation fits into the world, may be a strengthening opportunity.