Aydin Arici, MD

  • Professor of Obstetrics, Gynecology, and Reproductive Sciences

Aydin Arici, MD, is Professor of Obstetrics, Gynecology and Reproductive Sciences. His clinical interests include IVF, infertility, endometriosis, implantation, myomas, and uterine anomalies. Dr. Arici is a board certified specialist in Obstetrics and Gynecology and in Reproductive Endocrinology.

Dr. Arici received his medical degree from Istanbul Medical School in Turkey, and completed a residency in Obstetrics and Gynecology at Columbia University, College of Physicians and Surgeons, in New York City. His postgraduate training also included a fellowship in Reproductive Endocrinology and Infertility at the University of Texas Southwestern Medical Center in Dallas. He served as Director of Reproductive Endocrinology and Infertility at the Yale University School of Medicine for seven years.

Dr. Arici has been the recipient of many National Institutes of Health and pharmaceutical industry-sponsored research grants. More than 300 articles by Dr Arici have been published in leading journals. He is the Senior Editor of the book titled ‘Non-invasive Management of Gynecologic Disorders’, and he is the Series Editor of the Gynecology in Practice series.

Research interests
Endometriosis; Gynecology; Infertility; Obstetrics; Peritoneal Cavity; Reproductive Techniques; Cytokines; Chemokines
Research summary

Endometriosis is one of the most common benign diseases in reproductive aged women. It still remains one of the most enigmatic disorders in gynecology and in addition to infertility, endometriosis may also cause severe pelvic pain. Although retrograde menstruation is a nearly universal phenomenon, the prevalence of endometriosis suggests that other factors, such as immunologic changes, may determine a woman's susceptibility to endometriosis.

The goal of our work is to understand and identify the factors present in the peritoneal environment that may help explain the development of endometriosis. We have previously shown that the peritoneal environment in women with endometriosis has characteristics of preinflammatory tissue. There is an elevation of monocyte chemotactic protein-1 and interleukin-8 in the peritoneal cavity and these chemoattractant cytokines may play a role in the pathogenesis of endometriosis. The purpose of our work is to identify the role of these chemokines in the disease process and pathophysiology associated with endometriosis.

Education
  • MD, Istanbul University, 1979
Publications
  • Luk J, Seval Y, Kayisli UA, Ulukus M, Ulukus CE, Arici A, Regulation of Interleukin-8 Expression in Human Endometrial Endothelial Cells: a Potential Mechanism for the Pathogenesis Of Endometriosis., The Journal of Clinical Endocrinology and Metabolism, 90(3):1805-11, Mar 2005
  • Kayisli UA, Guzeloglu-Kayisli O, Arici A, Endocrine-immune Interactions in Human Endometrium., Annals of the New York Academy of Sciences, 1034, 50-63, Dec 2004
  • Halis G, Arici A, Endometriosis and Inflammation in Infertility., Annals of the New York Academy of Sciences, 1034, 300-15, Dec 2004 Abstract
  • Bukulmez O, Arici A, Luteal Phase Defect: Myth Or Reality., Obstetrics and Gynecology Clinics of North America, 31(4):727-44, ix, Dec 2004
  • Arici A, Bukulmez O, Phyto-oestrogens and the Endometrium., Lancet, 364(9451):2081-2, Dec 2004