Yale researchers in the section of Nephrology at the Yale School of Medicine are advancing our understanding of kidney disease, kidney injury and kidney-related disorders. Research focus areas include studies of the mechanisms of acute kidney injury and repair, molecular genetics of polycystic kidney disease and biomarkers in acute kidney injury and other kidney diseases. Yale researchers are at the forefront of discovering new mechanisms for kidney disease, such as the way sensory cilia impact cyst growth in polycystic kidney disease, that will lead to the next generation of therapies. They have also uncovered biomarkers that indicate a patient’s likelihood for developing acute kidney injury after cardiac surgery. Yale is home to two NIH-funded centers of kidney disease research excellence, the George M. O’Brien Kidney Center at Yale and the Yale Center for the Study of Polycystic Kidney Disease.