Metabolic Disease

(Image courtesy of Shutterstock)

Researchers in the Endocrinology & Metabolism division at Yale are reaching new understandings of diabetes and obesity and developing new therapies to improve patient health. Metabolic Syndrome describes a collection of disorders that includes obesity and diabetes, is the leading cause of chronic liver disease in the western world and raises one’s risk of heart disease and stroke. It is estimated that up to 30 million people suffer from metabolic syndrome, or non-alcoholic fatty liver disease, in the United States alone. Yale researchers have found that these diseases can be triggered by proteins disrupting microbes in the stomach. They have also uncovered the way the body’s metabolism impacts higher brain function, such as memory, and have discovered novel ways for disrupting the biological underpinnings of disorders that can predispose a person to type 2 diabetes.