There is transformative work happening in Yale’s Department of Immunobiology, one of the first university departments in the country devoted specifically to the immune system. The Yale Immunobiology Graduate Program is the top-ranked immunology graduate program in the United States. The researcher who helped found the department, Richard Flavell, still serves as its chair and works closely with Ruslan Medzhitov, the David W. Wallace Professor of Immunology, on pioneering contributions to the field. World-renowned researchers at Yale are leading to major advances in innate and adaptive immunity, and uncovering the molecular links between inflammation and chronic illnesses like cardiovascular disease, type 2 diabetes, allergies and asthma and Alzheimer’s disease. They are also discovering the role of inflammation in many age-related diseases, including arthritis and diabetes, and locating the triggers that can be turned off to control this inflammation and improve the life and health of the aging population.