- Leptospira is a major veterinary pathogen and can cause a life-threatening disease in humans.
- Current vaccines provide limited protective value.
- Yale researchers have generated a live, attenuated strain that provides significant protective immunity.
- Vaccination with this strain protects against a lethal challenge with various live Leptospira species.
- OCR6320 is a safe and efficacious novel vaccine candidate for the treatment of Leptospira infections.