Novel Therapeutic for Pulmonary Arterial Hypertension

OCR Number: 
OCR 5799
Description: 
  • Pulmonary arterial hypertension (PAH) has limited treatment options with 40-50% mortality within 3 years of diagnosis.
  • Identification of novel therapeutic targets remains a critical unmet medical need for this disease.
  • The global market for PAH is expected to grow to over $3.5 billion by 2016.
  • MicroRNAs (miRs) 424 and 503 are effective in human and animal models of PAH (see figure).
  • miRs 424 and 503 may be the basis for effective therapeutics for PAH.
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