Diagnostic Test for Acute Kidney Injury

OCR Number: 
OCR 5475
Description: 
  • In the US alone, there are at least 17 million cases of acute kidney injury (AKI) in hospitalized patients each year.
  • This diagnosis is associated with a high mortality rate of 45-80%.
  • YKL-40 is a protein-based biomarker for renal disease and a predictor of kidney allograft success.
  • This diagnostic test can rapidly identify patients who are at greatest risk of sustained renal failure and in need of subsequent dialysis.
Publications: 
Schmidt, I. M., Hall, I. E., Kale, S., Lee, S., He, C. H., Lee, Y., … & Cantley, L. G. (2013). Chitinase-like protein Brp-39/YKL-40 modulates the renal response to ischemic injury and predicts delayed allograft function. Journal of the American Society of Nephrology, 24(2), 309-319. [PubMed]
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