- A small-molecule named “antibody-recruiting molecule targeting HIV-1 (analog 3)” (ARM-H-3) targeted for the treatment of HIV (240nM HIV antagonist).
- Specifically both HIV (or HIV-infected CD4 T cells) and endogenous, well characterized, antibodies (anti-DNP).
- Blocks HIV entry into cells as well as recruits antibodies.
- Results in destruction of HIV and/or HIV-infected cells.
- Provides advantages over protein-based therapeutics, such as large-scale production capabilities and low cost.
- ARM-H-3 is a soluble drug-like compound derivative of a known HIV antagonist.